Luxury Hotels in Panama City, Panama

Exclusively curated and verified luxury accommodations in Panama City, Panama
Check-in
20May2025Select date
Check-out
21May2025Select date
Rooms and Guests2 Guests, 1 Room
View map
41-60 out of 89
Sort by: high popularity
  • Price: low to high
  • Price: high to low
  • Guest rating: high to low
  • Popularity: high to low
8.2
Great
MapClose to Panama Canal4km
  • On-site casino and vibrant nightlife
  • Outdoor pool and tropical garden courtyard
  • Fine dining at Lila Restaurant with views
  • Outdoor pool
  • Fitness centre
  • On-site casino
Hotel with diverse dining and entertainment options
FromUS$ 64 /nightSelect
8.2
Great
MapExclusive Obarrio district300m
  • Stylish rooftop pool with city views
  • Fine dining restaurant and cocktail lounge
  • Well-equipped health club with spa treatments
  • Rooftop pool
  • Fine dining
  • Health club
Luxury boutique hotel offering contemporary urban elegance
FromUS$ 85 /nightSelect
8.2
Great
MapClose to the financial district500m
  • Outdoor swimming pool open year-round
  • Restaurant serving Japanese cuisine
  • Free on-site parking available
  • Outdoor pool
  • On-site restaurant
  • 24-hour reception
Hotel offering modern rooms near financial district
FromUS$ 49 /nightSelect
MapAdjacent to Multiplaza Mall0m
  • On-site spa offers rejuvenating treatments
  • Outdoor pool for leisure and relaxation
  • Diverse dining options available on-site
  • On-site Spa
  • Outdoor Pool
  • Dining Options
Modern hotel with premium amenities and vibrant atmosphere
FromUS$ 147 /nightSelect
8.2
Great
MapHeart of the Financial District350m
  • Rooftop pool with skyline views
  • On-site fine dining restaurant
  • Modern fitness center available
  • Rooftop pool
  • Fitness center
  • On-site dining
Premier hotel for business and leisure travelers in Panama City
FromUS$ 69 /nightSelect
8.2
Great
MapIn Panama's Financial District300m
  • Outdoor pool with city views
  • Modern suites with kitchens
  • 24-hour reception and security
  • Outdoor pool
  • Fitness center
  • Event spaces
Hotel with full-service amenities in vibrant location
FromUS$ 133 /nightSelect
8.6
Great
MapHistoric Casco Viejo neighborhood150m
  • On-site restaurant serving diverse cuisine
  • 24-hour front desk for guest convenience
  • Air-conditioned rooms with modern amenities
  • On-site restaurant
  • 24-hour reception
  • Hot tub
Boutique hotel in the vibrant heart of Panama City
FromUS$ 86 /nightSelect
8.2
Great
MapBusiness district300m
  • Rooftop pool with panoramic views
  • Carmenére Restaurant serving international cuisine
  • Fitness center and business center onsite
  • Rooftop pool
  • Business center
  • Fitness center
Modern hotel with contemporary suites and rooftop amenities
FromUS$ 48 /nightSelect
8.0
Great
MapNear Financial District300m
  • Outdoor pool with stunning views
  • 24-hour fitness center available
  • On-site restaurant with local cuisine
  • Business center
  • Outdoor pool
  • Fitness center
Hotel with modern amenities in Panama's Financial District
FromUS$ 95 /nightSelect
8.2
Great
MapGreenwich Village-like neighborhood300m
  • Outdoor swimming pool
  • Multiple dining options
  • 24-hour reception
  • Outdoor Pool
  • Fitness Centre
  • On-site Restaurant
Hotel with diverse dining and recreation options
FromUS$ 36 /nightSelect
8.4
Great
MapHistoric Casco Viejo neighborhood100m
  • Unique suites with private balconies
  • Personalized local experiences offered
  • Family-friendly atmosphere and amenities
  • Bicycle Rental
  • In-House Spa
  • Pet-Friendly
Boutique hotel celebrating Panama's rich culture
FromUS$ 304 /nightSelect
8.2
Great
MapHeart of financial district0m
  • Outdoor swimming pool and on-site spa
  • International dining at the on-site restaurant
  • Located in the city's financial district
  • Outdoor pool
  • On-site spa
  • Restaurant
Hotel with exceptional spa services and dining options
FromUS$ 47 /nightSelect
8.0
Great
MapFinancial district dining options240m
  • Stunning city views from modern rooms
  • Located in Panama's financial district
  • Meeting rooms with advanced technology
  • Meeting Rooms
  • Fitness Centre
  • 24-hour Reception
A hotel merging modern comfort with cultural richness
FromUS$ 50 /nightSelect
8.2
Great
MapHeart of Casco Viejo300m
  • On-site spa with hot tub amenities
  • Dining featuring festive menus and views
  • Bicycle rentals available for exploration
  • On-site Spa
  • Dining Experience
  • Bicycle Rentals
Boutique hotel offering upscale amenities in historic Casco Viejo
FromUS$ 128 /nightSelect
8.2
Great
MapTropical rainforest setting2km
  • Two outdoor pools with rainforest views
  • On-site golf course and nature trails
  • On-site spa and wellness services
  • Outdoor pools
  • On-site spa
  • Golf course
Resort featuring golf, nature trails, and spa services
FromUS$ 36 /nightSelect
8.2
Great
MapMultiplaza Shopping Mall200m
  • Outdoor plunge pool for relaxation
  • Diverse dining options on-site
  • Convenient access to shopping malls
  • On-site restaurants
  • Fitness center
  • Business center
Hotel featuring vibrant dining and leisure options for travelers
FromUS$ 86 /nightSelect
8.4
Great
MapClose to Panama Convention Center10km
  • Panoramic bay views from all rooms
  • On-site restaurant serving international cuisine
  • Outdoor pool with breathtaking vistas
  • Outdoor pool
  • On-site restaurant
  • Gym with views
Hotel combining luxury, modernity, and historical charm
FromUS$ 67 /nightSelect
8.4
Great
MapNear Cinta Costera200m
  • Refreshing outdoor swimming pool
  • Game room with billiards
  • Comfortable shared and private rooms
  • Swimming Pool
  • Game Room
  • On-site Bar
Vibrant hostel offering adventure and relaxation in Panama
FromUS$ 11 /nightSelect
8.2
Great
MapIn the historic Casco Viejo neighborhood200m
  • Outdoor swimming pool with stunning views
  • On-site spa offering various treatments
  • Restaurant serving diverse dining options
  • Outdoor pool
  • On-site spa
  • Fitness center
Luxury hotel in the heart of historic Panama City
FromUS$ 385 /nightSelect
8.2
Great
Map2.2 mi from City Center1700 yd from Canal Museum of Panama
FromUS$ 20 /nightSelect

Price range for luxury hotels in Panama City

Explore a world of exceptional accommodations, from affordable stays to lavish retreats, with prices tailored to every luxury traveler's ideal getaway.

⬆️ The highest price
US$ 385
⬇️ The lowest price
US$ 11
💸 Average price for
5-star hotels
US$ 135
4-star hotels
US$ 89

Luxury hotels in Panama City

Verified guest reviews from the past 12 months

Panama Skyline Elegance:
JW Marriott Panama
Cultural Heritage Luxury:
Sofitel Legend Casco Viejo Panama City
Natural Retreats:
Summit Rainforest Golf Resort & All Inclusive
Business District Sophistication:
Marriott Panama Hotel - Albrook
Vibrant City Life:
Megapolis Hotel Panama
Casino and Nightlife Hub:
Veneto Hotel & Casino
Exceptional Dining Experiences:
Bristol Panama A Registry Collection Hotel
Boutique Charm and Comfort:
American Trade Hotel
Family Friendly Getaways:
Riu Plaza Panama

How to get to Panama City

Explore the finest transport options for effortless navigation

Airports
Tocumen International (PTY)
Paitilla (PAC)
Contadora (OTD)

FAQs about luxury hotels in Panama City

Our answers will guide you to an effortless luxury experience

What are the most family-friendly luxury hotels in Panama City?
Riu Plaza Panama and Dreams Playa Bonita All Inclusive offer family-centric amenities, such as children’s pools and activities. They also provide spacious accommodations suitable for families.
Which luxury hotels are best for couples in Panama City?
Sofitel Legend Casco Viejo and The Santa Maria, A Luxury Collection Hotel & Golf Resort, are perfect for couples, offering romantic dining, spa services, and intimate atmospheres.
What luxury hotels are closest to popular landmarks in Panama City?
The Central Hotel Panama in Casco Viejo is only a 5-minute walk to the Panama Canal Museum. Also, the Aloft Panama, situated in a modern district, is close to the Multiplaza Mall, just 10 minutes away.
Which luxury hotel has the best guest ratings in Panama City?
Bristol Panama, A Registry Collection Hotel, frequently receives top ratings for excellent service and high-quality amenities, often scoring above 9/10 from guests.

Luxury Hotels Overview in Panama City

This guide provides a compact overview of 73 luxury hotels in Panama City, focusing on key details such as pricing, proximity to attractions, and best times to book.

Typical nightly rates range from $150 to $450.

Peak travel seasons are December to April.

Local taxes add 10% to your total bill.

Most luxury hotels are within 1-3 miles of the Casco Viejo historic district.

Book at least 1-2 months in advance for the best rates.

Check-in
20May2025Select date
Check-out
21May2025Select date
Rooms and Guests2 Guests, 1 Room